[Gate-users] Internal dosimetry 131-Iodine

[Nicollas Goncalves Cavedini]

Dear Maikol, thank you very much for the answer!

*Best regards,*

*Nícollas Gonçalves Cavedini*
Bachelor of Medical Physics (PUCRS)
Master's Student in Electrical Engineering - PPGEE (PUCRS)
CV: http://lattes.cnpq.br/7248406497106855
Contact: +55 (51) 99922-9957
Porto Alegre, Brazil.





Em qui, 18 de abr de 2019 às 04:59, Maikol Salas Ramirez <mmsalas at gmail.com>
escreveu:

> Hi Nicollas
>
> 1- One option is to calculate the S-Value (Gy/(MBq-s)) in each voxel (or
> organ) of your phantom. Mainly it means to put the source in the group of
> voxels or organs that you consider is going to be locate the source and run
> a simulation.
> Then if you have a bio-kinetic curve (Activity Vs. Time) for each organ,
> the integral will have unit of MBq-s. Then you can multiply your voxels for
> this value.
>
> 2- If you already has bio-distribution (activity distribution images) of
> the source, run a simulation for each time point, therefore each voxel will
> have unit of Gy/s. Again you should calculate the TIAC value for the
> bio-kinetic curve (Activity/Administered-Activity Vs. Time) the integral
> will have unit of seconds (s).
>
> 3- Last option if you have a full decay profile (Activity Vs. Time) of
> your source in the organs of interest you can run a fun simulation, which
> include the activity decay.
>
> All are equivalent, it depends of the information that you already have.
> The tricky part is to find the way to validate your calculations. I
> recommend you, just chose that option that better fit with your experiment,
> and first try all with a simple geometry (sphere) and compare with manually
> calculation then go for a larger simulation.
>
> Best regards
> Maikol
>
> El mié., 17 abr. 2019 a las 20:30, Nicollas Goncalves Cavedini (<
> nicollas.cavedini at acad.pucrs.br>) escribió:
>
>> Hello, dear gate users!
>> I would like to simulate an iodine therapy using voxelized phantom
>> (Golem). My question is, do i need to simulate the entire therapy (7
>> half-lifes)? how can i do this?
>>
>> *Best regards,*
>>
>> *Nícollas Gonçalves Cavedini*
>> Bachelor of Medical Physics (PUCRS)
>> Master's Student in Electrical Engineering - PPGEE (PUCRS)
>> CV: http://lattes.cnpq.br/7248406497106855
>> Contact: +55 (51) 99922-9957
>> Porto Alegre, Brazil.
>>
>>
>>
>>
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>> Gate-users mailing list
>> Gate-users at lists.opengatecollaboration.org
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>
>
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