[Gate-users] How to simulate Lu-176 in LSO crystal

[Albert Grace Lieu]

Dear Emilie,

Thank you for sharing your thoughts and help. I definitely know using any
ion source my simulation can be 10 times slower. Lu176  decay creates
multiple gammas during de-exictation as shown in the decay scheme below. I
guess I can call the noise module multiple times to simulate different
gamma emissions. But how to simulate the bata decay and annihilations with
the noise module? Also the branching ratios?

Thanks a lot.
Zhengzhi
[image: Screenshot from 2020-06-11 09-47-30.png]

On Thu, Jun 11, 2020 at 12:26 PM Emilie Gaudin <
Emilie.Odette.Gaudin at usherbrooke.ca> wrote:

> Hi Zhengzhi,
>
> Maxime was absolutely right saying the noise module simulate the intrinsic
> radioactivity. It was well established and demonstrated since many years
> (just google it).
>  You only need to define your noise (mean std lambda) as you know how
> your detector react.
> You can create a source for each crystal but why tho ... In my opinion
> it's a terrible ideas since your sources are user dependent and  your
> simulations will be much slower.
>
> Have a nice day !
>
> Émilie
>
> ------------------------------
> *De :* Gate-users <gate-users-bounces at lists.opengatecollaboration.org> de
> la part de Arnulfo Martinez-Davalos <arnulfo at fisica.unam.mx>
> *Envoyé :* 11 juin 2020 15:03
> *À :* gate-users at lists.opengatecollaboration.org <
> gate-users at lists.opengatecollaboration.org>
> *Objet :* Re: [Gate-users] How to simulate Lu-176 in LSO crystal
>
>
> Dear Zhengzhi,
>
> Please let me call your attention to a series of papers our group has
> published regarding the intrinsic radioactivity in LYSO crystals due to
> Lu-176:
>
> - Alva-Sánchez H, et al., “Understanding the intrinsic radioactivity
> energy spectrum from 176Lu in LYSO/LSO scintillation crystals”, Nature Sci.
> Rep. (2018) 8:17310 (https://doi.org/10.1038/s41598-018-35684-x
> <https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1038%2Fs41598-018-35684-x&data=02%7C01%7Cemilie.odette.gaudin%40usherbrooke.ca%7Cc1f6a6661e3e4b40b85d08d80e3a1df7%7C3a5a8744593545f99423b32c3a5de082%7C0%7C0%7C637274990921014034&sdata=Yz4MiMo6YwF6srTIDNTo9vV5ek1xIAfl4d4ymbv%2B6WU%3D&reserved=0>
> )
> - Enríquez-Mier-y-Terán FE, et al., “GATE simulation of the intrinsic
> radioactivity in LYSO scintillation crystals”, Nucl. Instr. Meth. B 454
> (2019) 1-5. (https://doi.org/10.1016/j.nimb.2019.06.001
> <https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.nimb.2019.06.001&data=02%7C01%7Cemilie.odette.gaudin%40usherbrooke.ca%7Cc1f6a6661e3e4b40b85d08d80e3a1df7%7C3a5a8744593545f99423b32c3a5de082%7C0%7C0%7C637274990921024033&sdata=xihfZcHk7tAb9Wfx%2Fz4hbhENH%2BGW%2F0xk2fY5fOvvO8Y%3D&reserved=0>
> ).
>
> - Enríquez-Mier-y-Terán FE, et al., “Coincidence energy spectra due to the
> intrinsic radioactivity of LYSO scintillation crystals”, EJNMMI Physics
> (2020) 7:21 (https://doi.org/10.1186/s40658-020-00291-1
> <https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2F10.1186%2Fs40658-020-00291-1&data=02%7C01%7Cemilie.odette.gaudin%40usherbrooke.ca%7Cc1f6a6661e3e4b40b85d08d80e3a1df7%7C3a5a8744593545f99423b32c3a5de082%7C0%7C0%7C637274990921024033&sdata=zYkJkVLbAnyMLMvaCisYCcaLHeHaN43dbbk3DdqAeRw%3D&reserved=0>
> ).
>
> For the second and third ones we actually used the ion source for Lu-176
> in GATE v8.1, and it worked just fine. I hope you find this information
> useful.
>
> Best regards,
> Arnulfo
>
> Arnulfo Martinez-Davalos, PhD
> Instituto de Fisica, UNAM
> A.P. 20-364
> 01000 CDMX
> MEXICO
>
> On 2020-06-11 12:09 AM, Albert Grace Lieu wrote:
>
> Dear Gate users and developers,
>
> There are a couple of papers [1
> <https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Faapm.onlinelibrary.wiley.com%2Fdoi%2Fabs%2F10.1118%2F1.4824694&data=02%7C01%7Cemilie.odette.gaudin%40usherbrooke.ca%7Cc1f6a6661e3e4b40b85d08d80e3a1df7%7C3a5a8744593545f99423b32c3a5de082%7C0%7C0%7C637274990921034020&sdata=NpKzPik242hOOn8fcm1BBvkPABRxzwBaNdSQFBBave4%3D&reserved=0>
> ,2
> <https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fieeexplore.ieee.org%2Fdocument%2F5751205&data=02%7C01%7Cemilie.odette.gaudin%40usherbrooke.ca%7Cc1f6a6661e3e4b40b85d08d80e3a1df7%7C3a5a8744593545f99423b32c3a5de082%7C0%7C0%7C637274990921034020&sdata=JHa%2F1Vlq6s%2FpXSz6ReUa1EpWos1YriNuXMKGIwZaeN4%3D&reserved=0>]
> addressing the importance of adding the simulation of Lu-176 in Lutetium
> based crystal in GATE simulation. I try to do this to my simulated PET
> system that has thousands of pieces of crystals (created with linear and
> cubic array repeater). My general idea of implementing this is to create a
> Lu176 ion source and then attach it to my crystals. However,  when I do:
>
> /gate/source/Lu176/attachTo Crystal
>
> the Lu176 is only attached to a single piece of crystal (which can be
> visualized with /gate/source/Lu176/visualize 1000 red 3).  Has anyone
> implemented this before? Could you please share your thoughts?
>
> Thanks a lot. Greatly appreciated.
>
> Zhengzhi
>
> _______________________________________________
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>
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