[Gate-users] Divergence between GATE simulation and the reality

[Julien Salvadori]

Greetings,

I had the same problem when I modeled the Vereos PET, namely an
overestimation of the NEMA sensitivity by about 25%.

In my case, this was because I had not modeled the intrinsic detection
efficiency. (the transfer efficiency of the crystal and the quantum
efficiency of the photo-detector).

Did you take this parameter into account ?

If you don't have the manufacturer's information, you can estimate it by
following the methodology described by Guez et al (2008), which we used to
estimate the efficiency of the Vereos PET (Salvadori et al (2020)).

Best

Julien Salvadori

Le ven. 29 mai 2020 à 19:33, Albert Grace Lieu <albertnew2018 at gmail.com> a
écrit :

> Dear GATE users,
>
> I have modeled a real PET system in GATE as close to the real system as I
> can. However, during the noise equivalent count collaboration, GATE is
> always much better (about 50%) than the real system. After lots of effort,
> we looked at the results of the NEMA sensitivity experiment (very low dose,
> ~500 uci) and found that GATE collected about 25% more counts than the real
> system.
>
> I was wondering if there is some calibration work done between GATE
> simulation and reality. Could someone give any help on how to further debug
> or make clear what causes this discrepancy between simulation and reality?
>
> Thanks a lot.
> Zhengzhi
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