[Gate-users] how can I apply TOF information on images

[Zhao, Wei]

Dear  Hanieh,

To my knowledge, TOF can only be applied to list-mode OSEM 
reconstruction framework. After you extract the tof information using a 
root script, you have to incorporate the information into the 
reconstruction framework. Specifically, suppose  a_ij is the probability 
that an event generated in pixel j is detected by the i_th measurement. 
Then the TOF reconstruction framework have to replace a_ij with

a_ij * (1/(sqrt(2*pi)*sigma))*exp(-(x-x_i)^2/(2*sigma^2))

Here x is the annihilation point calculated using the time information. 
The physical meaning of the above equation is to constraint the location 
of backprojection and forward projection during reconstruction.

I believe there are a lot of paper about the TOF reconstruction 
framework and you can get more from these papers.

Best
Wei

On 11/18/2015 7:00 PM, 
gate-users-request at lists.opengatecollaboration.org wrote:
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>     1. Re: how can I apply TOF information on images (Hanieh)
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> ----------------------------------------------------------------------
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> Message: 1
> Date: Wed, 18 Nov 2015 15:08:52 +0330
> From: Hanieh <Hanieh_jozi69 at yahoo.com>
> To: STRYDHORST Jared <Jared.STRYDHORST at cea.fr>
> Cc: "gate-users at lists.opengatecollaboration.org"
> 	<gate-users at lists.opengatecollaboration.org>
> Subject: Re: [Gate-users] how can I apply TOF information on images
> Message-ID: <A207DF27-9428-4213-A481-7F31B46ECDDD at yahoo.com>
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>
> So is it true to say: " This timing information (TOF) is then taken into account during the fully 3D reconstruction of the data. And for example:I will convert the list mode to a ROOT format to produce sinograms. "
>
> Je vous  remercie.
>
> Hanieh jozi
> Ms.student in Medical Radiation Engineering
>
> Amiti?s
> Envoy? de mon iPhone
>
>> Le 17 nov. 2015 ? 14:46, STRYDHORST Jared <Jared.STRYDHORST at cea.fr> a ?crit :
>>
>> I don't think any of the built-in methods for exporting sinograms or list mode data include TOF information. The time of each single is stored for the coincidences in the root output, so the TOF list mode or sinogram data can be extracted, but it requires writing a root script to convert the root data to the output format you want.
>>
>> Jared STRYDHORST
>>
>> Laboratoire Imagerie Mol?culaire In Vivo (IMIV)
>> UMR 1023 Inserm/CEA/Universit? Paris Sud - ERL 9218 CNRS
>> CEA/I2BM/Service Hospitalier Fr?d?ric Joliot
>> 4, place du G?n?ral Leclerc
>> 91401 ORSAY Cedex
>>
>> http://i2bm.cea.fr/dsv/i2bm/shfj/imiv
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