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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:EN-US">Hi Ville-Veikko<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:EN-US">Thank you for your reply. The relevants macs are attached to this email. I have 8 mains in total (one for each core) which are identical
apart from the first one has visualisation. The current offset was just something I was trying but I can’t seem to get any of the numbers to truly work.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:EN-US">Thank you<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:EN-US"><o:p> </o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#006871">Mark Baker<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#006871">Principal Clinical Scientist<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#006871">Imaging Physics (Ionising)<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#006871">The Clatterbridge Cancer Centre NHS Foundation Trust<o:p></o:p></span></p>
<p class="MsoNormal"><i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#006871">(he, him)<o:p></o:p></span></i></p>
<p class="MsoNormal"><b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#006871"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#006871">CCCW Tel: 0151 556 5030
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#006871">CCCL Tel: 0151 318 8438<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#006871">Email:
</span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#4472C4"><a href="mailto:mark.baker23@nhs.net"><span style="color:#4472C4">mark.baker23@nhs.net</span></a></span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#006871">
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#4472C4"><a href="https://teams.microsoft.com/l/chat/0/0?users=mark.baker23@nhs.net"><span style="color:#4472C4">Microsoft Teams (click here)</span></a></span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:EN-US"><o:p> </o:p></span></p>
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<p class="MsoNormal"><b><span lang="EN-US" style="font-size:11.0pt;font-family:"Calibri",sans-serif">From:</span></b><span lang="EN-US" style="font-size:11.0pt;font-family:"Calibri",sans-serif"> Ville-Veikko Wettenhovi <ville-veikko.wettenhovi@uef.fi>
<br>
<b>Sent:</b> 16 June 2022 14:46<br>
<b>To:</b> BAKER, Mark (THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST) <mark.baker23@nhs.net>; gate-users@lists.opengatecollaboration.org<br>
<b>Subject:</b> Re: Voxelised Source Placement Confusion<o:p></o:p></span></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black">Hi Mark,<o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black"><o:p> </o:p></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black">Moving the voxelized source by half of each dimension should indeed work and has worked in the cases where I've used voxelized source. Could you share the
part of the macro where you define and move the voxelized source? <o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black"><o:p> </o:p></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black">Another way to determine the positioning could be to form the "ground truth" image of the trues, i.e. an image where the coincidences are accumulated based
on their source locations. Then compare that image to the attenuation image from the attenuation map actor (both with the same dimensions).<o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black"><o:p> </o:p></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black">Regards,
<o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black">Ville-Veikko Wettenhovi<o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-family:"Calibri",sans-serif;color:black"><o:p> </o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black">From:</span></b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black"> Gate-users <<a href="mailto:gate-users-bounces@lists.opengatecollaboration.org">gate-users-bounces@lists.opengatecollaboration.org</a>>
on behalf of BAKER, Mark (THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST) <<a href="mailto:mark.baker23@nhs.net">mark.baker23@nhs.net</a>><br>
<b>Sent:</b> Thursday, June 16, 2022 16:27<br>
<b>To:</b> <a href="mailto:gate-users@lists.opengatecollaboration.org">gate-users@lists.opengatecollaboration.org</a> <<a href="mailto:gate-users@lists.opengatecollaboration.org">gate-users@lists.opengatecollaboration.org</a>><br>
<b>Subject:</b> [Gate-users] Voxelised Source Placement Confusion</span> <o:p></o:p></p>
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<p class="MsoNormal"> <o:p></o:p></p>
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<p class="xmsonormal">Hi all<o:p></o:p></p>
<p class="xmsonormal"> <o:p></o:p></p>
<p class="xmsonormal">I raised this query a while (or one similar) but unfortunately, I’ve not managed to get back around to my project for a while. In short, I can’t get good alignment between my CT and PET images. My understanding is that the voxelised PET
source image should be offset by half of its size to account for it being placed in the corner of the world instead of the centre where the CT image is place. My world is 1 1 2 m and my CT data is 780 780 693 mm (512x512x213 matrix). My PET data is 814.568
814.568 639 mm (200x200x213 matrix).<o:p></o:p></p>
<p class="xmsonormal"> <o:p></o:p></p>
<p class="xmsonormal">I think I was a bit confused at first, and was moving the PET source by half of its own size but then I re-read the ReadTheDocs and I think it is suggesting that I actually need to move the PET image by half of the world size (setPosition
-500 -500 -1000 mm) but this results in a large offset. I’ve tried various combinations of half the size of the world, half the size of the PET data etc. and I think I’m just going around in circles now. Logically, I feel like the solution is that I move half
of the world size at first to move the corner of the PET data into the centre of the world, then back by half of the PET image to put the centre of the PET in the centre of the world, but it is still offset. Any suggestions, as I’m tearing my hair out a little
now.<o:p></o:p></p>
<p class="xmsonormal"> <o:p></o:p></p>
<p class="xmsonormal"> <o:p></o:p></p>
<p class="xmsonormal">Additionally, in order to test where the positioning is correct, I’m relying on the generation of secondary electrons within the water phantom in my image and looking at the NbofHits file produced. This works fine when the difference is
obvious between the two, but I wonder if there is a better way to see the isocentre in order to 100% confirm it is correct? The reason I use secondary electrons is that positrons and gammas flood the image making it impossible to see the underlying CT data,
plus I expect the secondary electrons to largely be created in the water and not air.<o:p></o:p></p>
<p class="xmsonormal"> <o:p></o:p></p>
<p class="xmsonormal">Thank you in advance!<o:p></o:p></p>
<p class="xmsonormal"> <o:p></o:p></p>
<p class="xmsonormal"><b><span style="color:#006871">Mark Baker</span></b><o:p></o:p></p>
<p class="xmsonormal"><span style="color:#006871">Principal Clinical Scientist</span><o:p></o:p></p>
<p class="xmsonormal"><span style="color:#006871">Imaging Physics (Ionising)</span><o:p></o:p></p>
<p class="xmsonormal"><span style="color:#006871">The Clatterbridge Cancer Centre NHS Foundation Trust</span><o:p></o:p></p>
<p class="xmsonormal"><i><span style="color:#006871">(he, him)</span></i><o:p></o:p></p>
<p class="xmsonormal"><b><span style="color:#006871"> </span></b><o:p></o:p></p>
<p class="xmsonormal"><span style="color:#006871">CCCW Tel: 0151 556 5030 </span>
<o:p></o:p></p>
<p class="xmsonormal"><span style="color:#006871">CCCL Tel: 0151 318 8438</span><o:p></o:p></p>
<p class="xmsonormal"><span style="color:#006871">Email: </span><span style="color:#4472C4"><a href="mailto:mark.baker23@nhs.net"><span style="color:#4472C4">mark.baker23@nhs.net</span></a></span><span style="color:#006871">
</span><o:p></o:p></p>
<p class="xmsonormal"><span style="color:#4472C4"><a href="https://eur03.safelinks.protection.outlook.com/?url=https%3A%2F%2Fteams.microsoft.com%2Fl%2Fchat%2F0%2F0%3Fusers%3Dmark.baker23%40nhs.net&data=05%7C01%7C%7Cf915f5c6550b432ebceb08da4f9bf88e%7C87879f2e73044bf2baf263e7f83f3c34%7C0%7C0%7C637909828551983408%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C2000%7C%7C%7C&sdata=2gNulx6%2Fbs%2FjQq1Ql9%2BTME07ATbeaYvixCr6%2BNmrgwM%3D&reserved=0"><span style="color:#4472C4">Microsoft
Teams (click here)</span></a></span><o:p></o:p></p>
<p class="xmsonormal"> <o:p></o:p></p>
<p class="xmsonormal"><i><span style="color:#006871">Honorary Lecturer, Dept. of Physics</span></i><o:p></o:p></p>
<p class="xmsonormal"><i><span style="color:#006871">University of Liverpool</span></i><o:p></o:p></p>
<p class="xmsonormal"><span style="color:#006871"> </span><o:p></o:p></p>
<p class="xmsonormal"><img border="0" width="624" height="163" style="width:6.5in;height:1.6979in" id="x_Picture_x0020_3" src="cid:image001.jpg@01D88192.F9CE12F0" alt="CCC email footer April 2021"><o:p></o:p></p>
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