<div dir="ltr">Hi Gate users, <div><br></div><div>I am validating the validity of DoseActor in GATE for radionuclide dosimetry application. Surprisingly, I found the Edep returned by DoseActor is about 7 times bigger than my hand calculated value, so does the dose returned by DoseActor. I could be wrong, but I double-checked everything I did and had been as prudent as I can before asking for suggestions here. </div><div><br></div><div>Here is what I did in GATE:</div><div><ul><li>Phantom: 101*101*101 voxelized tissue (
water equivalent) phantom, with a side of 2 mm for each voxel </li><li>Source: 10 mm radius sphere voxelized Lu177 source with a side of 2 mm for each voxel, and being placed in the center of the phantom</li><li>DoseActor: record dose, Edep, and export a mass image of the phantom (all 3D array)</li><li>ProductionAndStoppingActor: record the number of Lu177 generated in each voxel, indicated by Lu177-Stop
(3D array)
</li></ul><div> According to the user manual, "The unit of edep is MeV and the unit of dose is Gy". </div><div><br></div><div>Here is how I calculate the average of the energy of Lu177 in water, Lu177 is a beta emitter, the range of electron in water is way smaller than 2mm, thus it is stopped where is created. Given the branching ratio of Lu177, on average a single Lu177 disintegration would deposit 134.16 Kev (electrons only) or 162.95 Kev (electrons and gammas).</div><div><br></div><img src="cid:ii_klvt1d9c0" alt="RTEmagicC_Lu-177_decays.png.png" width="279" height="181" style="margin-right:0px"></div><div><br></div><div>However, when I divide Edep by Lu177-Stop, the energy per Lu177 disintegration returned by DoseActor is <font color="#ff0000">~1.0 Mev</font>, which <font color="#ff0000">7</font> times bigger than my hand calculated value. Is this an internal issue? I attach my Gate code for your review. </div><div><br></div><div><br></div><div>Thanks a lot for your help. </div><div>Sincere wishes, </div><div>Stay safe and healthy<br></div><div>Albert </div><div><div><br></div><div><br></div></div></div>