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<div dir="ltr" data-setdir="false">Hi Maria, </div><div dir="ltr" data-setdir="false"><br></div><div dir="ltr" data-setdir="false">You could start a simulation by setting a total number of primaries instead of time. Based on my experience with GATEv8.1, the transport of 20 million particles was found to provide sufficient statistical precision. See details in: <a href="https://meridian.allenpress.com/radiation-research/article-abstract/193/6/531/436368/The-Impact-of-Tissue-Type-and-Density-on-Dose?redirectedFrom=fulltext" class="enhancr_card_3691519457" target="_blank" rel="noreferrer noopener">The Impact of Tissue Type and Density on Dose Point Kernels for Patient-Specific Voxel-Wise Dosimetry: A Monte Carlo Investigation | Radiation Research | Allen Press</a></div><div><br></div><div id="ydp3b9ead41enhancr_card_3691519457" class="ydp3b9ead41yahoo-link-enhancr-card ydp3b9ead41yahoo-link-enhancr-not-allow-cover ydp3b9ead41ymail-preserve-class ydp3b9ead41ymail-preserve-style" style="max-width:400px;font-family:YahooSans, Helvetica Neue, Segoe UI, Helvetica, Arial, sans-serif" data-url="https://meridian.allenpress.com/radiation-research/article-abstract/193/6/531/436368/The-Impact-of-Tissue-Type-and-Density-on-Dose?redirectedFrom=fulltext" data-type="YENHANCER" data-size="MEDIUM" contenteditable="false"><a href="https://meridian.allenpress.com/radiation-research/article-abstract/193/6/531/436368/The-Impact-of-Tissue-Type-and-Density-on-Dose?redirectedFrom=fulltext" style="text-decoration:none !important;color:#000 !important" class="ydp3b9ead41yahoo-enhancr-cardlink" target="_blank" rel="noreferrer noopener"><table border="0" class="ydp3b9ead41card-wrapper ydp3b9ead41yahoo-ignore-table" cellpadding="0" cellspacing="0" style="max-width:400px"><tbody><tr><td width="400"><table border="0" class="ydp3b9ead41card ydp3b9ead41yahoo-ignore-table" cellpadding="0" cellspacing="0" width="100%" style="max-width:400px;border-width:1px;border-style:solid;border-color:rgb(224, 228, 233);border-radius:2px"><tbody><tr><td><table border="0" class="ydp3b9ead41card-info ydp3b9ead41yahoo-ignore-table" cellpadding="0" cellspacing="0" style="background:#fff;position:relative;z-index:2;width:100%;max-width:400px;border-radius:0 0 2px 2px;border-top:1px solid rgb(224, 228, 233)"><tbody><tr><td style="background-color:#ffffff;padding:16px 0 16px 12px;vertical-align:top;border-radius:0 0 0 2px"></td><td style="vertical-align:middle;padding:12px 24px 16px 12px;width:99%;font-family:YahooSans, Helvetica Neue, Segoe UI, Helvetica, Arial, sans-serif;border-radius:0 0 2px 0"><h2 class="ydp3b9ead41card-title" style="font-size: 14px; line-height: 19px; margin: 0px 0px 6px; font-family: YahooSans, Helvetica Neue, Segoe UI, Helvetica, Arial, sans-serif; color: rgb(38, 40, 42); max-width: 314px;">The Impact of Tissue Type and Density on Dose Point Kernels for Patient-...</h2><p class="ydp3b9ead41card-description" style="font-size: 12px; line-height: 16px; margin: 0px; color: rgb(151, 155, 167);"></p></td></tr></tbody></table></td></tr></tbody></table></td></tr></tbody></table></a></div><div><br></div><div dir="ltr" data-setdir="false">Also, I recommend using ~1 keV energy cuts in dose point kernel simulations. Cuts can be set by using:</div><div dir="ltr" data-setdir="false"><br></div><div dir="ltr" data-setdir="false"><div><div>/gate/physics/Gamma/SetCutInRegion world ... mm</div><div>/gate/physics/Electron/SetCutInRegion world ... mm</div><div><br></div><div>/gate/physics/Gamma/SetCutInRegion my_phantom ... mm </div><div>/gate/physics/Electron/SetCutInRegion my_phantom .. mm</div><div><br></div><div dir="ltr" data-setdir="false">Another important thing is an steplimiter, you could set it by using:</div><div dir="ltr" data-setdir="false"><br></div><div>/gate/physics/SetMaxStepSizeInRegion my_phantom ... mm</div><div>/gate/physics/ActivateStepLimiter e-</div><div><br></div></div><div dir="ltr" data-setdir="false">All other infos are described in the paper.</div><div dir="ltr" data-setdir="false"><br></div><div dir="ltr" data-setdir="false">Regards,</div><div dir="ltr" data-setdir="false">Ashok</div><br></div>
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On Tuesday, 9 February 2021, 09:19:23 am GMT-6, Maria Inês Ribeiro <mid.ribeiro@campus.fct.unl.pt> wrote:
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<div><div id="yiv8564264232"><div dir="ltr">Thank you so much. <div><br></div><div>It was supposed to be 100000 s. I just killed the simulation because it was taking too long. </div><div>I swapped to the normal ion source definition since fastY90 can't be used for dosimetry. </div><div><br></div><div>Do you recommend decreasing cut energy for photons and electrons?</div><div><br></div><div>Kind regards, </div><div>Maria </div></div><br><div class="yiv8564264232gmail_quote"><div dir="ltr" class="yiv8564264232gmail_attr">陈戈飞 <<a ymailto="mailto:xiaofeizaina@126.com" href="mailto:xiaofeizaina@126.com" target="_blank" rel="noreferrer noopener">xiaofeizaina@126.com</a>> escreveu no dia terça, 9/02/2021 à(s) 15:13:<br></div><blockquote class="yiv8564264232gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex;"><div><div id="yiv8564264232gmail-m_-973855092368961664contentDescription" style="line-height:1.5;text-align:justify;">
<div id="yiv8564264232gmail-m_-973855092368961664imail_extraContent">Hi maria
<br>The total time of your simulations is 10000s,right? If so, you only need to multiply by 1000(Gy->mGy) and divide 10000(time to 1s).
<br>And I recommend setting cut energy for beta and photon. Default is 10 mm.
<br>You'd better recheck the definition of fastY90. It can't be used for dose purposes.
<br>Thank you
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<div style="background-color:rgb(242,242,242);color:black;padding-top:6px;padding-bottom:6px;border-radius:3px;margin-top:45px;margin-bottom:20px;"><div style="font-size:14px;line-height:1.5;margin-left:10px;margin-right:10px;">On <span>02/09/2021 22:38</span>, <a style="text-decoration:none;color:rgb(42,151,255);" ymailto="mailto:mid.ribeiro@campus.fct.unl.pt" href="mailto:mid.ribeiro@campus.fct.unl.pt" target="_blank" rel="noreferrer noopener">Maria Inês Ribeiro</a> wrote: </div></div><blockquote id="yiv8564264232gmail-m_-973855092368961664ntes-iosmail-quote" style="margin:0px;"><div dir="ltr">Hi everyone, <div><br></div><div>I am attempting to compute a dose point kernel in soft tissue for a point source of Y90. I am using the fastY90 with an activity of 1 MBq. </div><div>I then ran 40.000 slices of 1 second and stored the dose. </div><div><br></div><div>My question is how do I convert my dose map (Gy) into the s values (mGy/(MBq.s)) for each voxel? </div><div><br></div><div>Here is my could in case it could help to support my question:</div><div><br></div><div>#===============================================================================<br># GEOMETRY<br>#===============================================================================<br><br>/gate/geometry/setMaterialDatabase data/GateMaterials.db<br><br>#WORLD ======================================<br>/gate/world/setMaterial Air<br>/gate/world/geometry/setXLength 50 mm<br>/gate/world/geometry/setYLength 50 mm<br>/gate/world/geometry/setZLength 50 mm<br><br>#LIVER ======================================<br>/gate/world/daughters/name liverPhantom<br>/gate/world/daughters/insert box<br>/gate/liverPhantom/setMaterial Liver<br>/gate/liverPhantom/geometry/setXLength 24.31 mm<br>/gate/liverPhantom/geometry/setYLength 24.31 mm<br>/gate/liverPhantom/geometry/setZLength 24.31 mm<br><br>#===============================================================================<br># PHYSICS<br>#===============================================================================<br><br>/gate/physics/addPhysicsList emstandard_opt3<br><br>#===============================================================================<br># DETECTORS<br>#===============================================================================<br><br>#DOSE ACTOR ==============================<br>#builds 3D images of:<br># - the energy deposited (edep in MeV)<br># - dose deposited (Gy)<br># - the number of hits in a volume<br><br>/gate/actor/addActor DoseActor VSV<br>/gate/actor/VSV/attachTo liverPhantom<br>/gate/actor/VSV/stepHitType random<br>/gate/actor/VSV/setSize 24.31 24.31 24.31 mm<br>/gate/actor/VSV/setPosition 0 0 0 cm<br>/gate/actor/VSV/setResolution 11 11 11<br>/gate/actor/VSV/enableEdep true<br>/gate/actor/VSV/enableUncertaintyEdep true<br>/gate/actor/VSV/enableSquaredEdep true<br>/gate/actor/VSV/enableDose true<br>/gate/actor/VSV/enableUncertaintyDose true<br>/gate/actor/VSV/enableSquaredDose true<br>/gate/actor/VSV/enableNumberOfHits true<br>/gate/actor/VSV/save output/VSV.mhd<br><br>#SIMULATION STATISTIC =====================<br>#this actos counts the number of steps, tracks, events, runs in the simulation<br><br>/gate/actor/addActor SimulationStatisticActor stat<br>/gate/actor/stat/save output/stat-VSV.txt<br>/gate/actor/stat/saveEveryNSeconds 60<br><br><br>#===============================================================================<br># INITIALISATION<br>#===============================================================================<br><br>/gate/run/initialize<br><br>/gate/random/setEngineName MersenneTwister<br>/gate/random/setEngineSeed auto<br><br>#===========================================================<br># SOURCE <br>#===========================================================<br><br># fastY90<br>/gate/source/addSource y90 fastY90<br>/gate/source/y90/setActivity 1. MBq<br><br>#=====================================================<br># START<br>#=====================================================<br><br>/gate/application/setTimeSlice 1. s<br>/gate/application/setTimeStart 0. s<br>/gate/application/setTimeStop 1000000. s <br>/gate/application/start<br></div><div><br></div><div><br></div><div>Thanks a lot for your attention, </div><div><br></div><div>Maria Inês</div><div><br></div><div><br></div><div><br></div><div><br></div><div><br></div></div>
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