<div dir="ltr">Hi Cassandra,<div><br></div><div>Thank you for your reply. I use the following standard definition for the physics list. I also put the definition of the I-124 point source below.</div><div>How do you set the energy cuts? Do you mean the production threshold: <a href="https://opengate.readthedocs.io/en/latest/cut_and_variance_reduction_technics.html?highlight=range%20cut#production-threshold">https://opengate.readthedocs.io/en/latest/cut_and_variance_reduction_technics.html?highlight=range%20cut#production-threshold</a></div><div><br></div><div># P H Y S I C S<br>/gate/physics/addPhysicsList emstandard<br>/gate/physics/addProcess RadioactiveDecay<br>/gate/physics/processList Enabled<br>/gate/physics/processList Initialized<br></div><div><br></div><div># S O U R C E: I-124<br>/gate/source/addSource pointsource<br>/gate/source/pointsource/gps/particle ion<br>/gate/source/pointsource/gps/ion 53 124 0 0<br>/gate/source/pointsource/gps/monoenergy 0. keV<br>/gate/source/pointsource/gps/angtype iso<br>/gate/source/pointsource/gps/mintheta 0 deg <br>/gate/source/pointsource/gps/maxtheta 180 deg<br>/gate/source/pointsource/gps/minphi -180 deg <br>/gate/source/pointsource/gps/maxphi 180 deg <br>/gate/source/pointsource/gps/centre 0 0 0 mm<br>/gate/source/pointsource/setActivity 30000000 Bq<br></div><div><br></div><div>Best,</div><div>Minh</div></div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Mon, Nov 9, 2020 at 11:21 PM Cassandra Miller <<a href="mailto:cassandramiller@phas.ubc.ca" target="_blank">cassandramiller@phas.ubc.ca</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex">Hi Minh,<br>
<br>
I don't have a solution to your problem, but is it possible that your <br>
energy cuts are too high and hence your positrons are stopping too early <br>
and depositing all of their energy? Also, what physics list are you <br>
using?<br>
<br>
Best,<br>
Cassandra<br>
<br>
On 2020-11-09 07:27, Minh Phuong Nguyen wrote:<br>
> Can anyone help me with this?<br>
> The inconsistency in the positron range simulation with GATE appears<br>
> to be an existing problem.<br>
> Several related posts in the gate-user archive have not received a<br>
> final answer either.<br>
> <br>
> Minh<br>
> <br>
> On Thu, Nov 5, 2020 at 10:29 AM Minh Phuong Nguyen <<a href="mailto:mipbkhn@gmail.com" target="_blank">mipbkhn@gmail.com</a>><br>
> wrote:<br>
> <br>
>> Dear GATErs,<br>
>> <br>
>> I simulated positron ranges for several isotopes such as F-18 and<br>
>> I-124 with GATE. The setup was very simple with a point source at<br>
>> the centre of a water environment (20-cm-radius sphere). The sphere<br>
>> was that large to make sure that the positrons do not escape the<br>
>> water volume.<br>
>> <br>
>> The obtained mean/max positron range from this simulation was<br>
>> shorter than what I found in literature. Then I tested with<br>
>> different GATE versions (8.0/ 9.0 with corresponding GEANT4 versions<br>
>> as stated in the GATE documentation), and different ways of defining<br>
>> the source (ion, e+, fastI124). I observed that the positron range<br>
>> result was not consistent when changing these parameters (attached<br>
>> figures).<br>
>> <br>
>> Looking at the range distributions (attached figures), GATE 8.0 with<br>
>> ion source produced a lot of annihilations near the decay locations<br>
>> (range ~ 0 mm). This was not the case with GATE 9.0 and e+ or<br>
>> fastI124 sources.<br>
>> <br>
>> Does anybody know:<br>
>> - why positron range from GATE is shorter than in literature?<br>
>> <br>
>> - which changes in the new GATE version makes the discrepancy in<br>
>> positron range simulation result?<br>
>> - what makes the difference in positron range between the ion source<br>
>> and other type sources?<br>
>> <br>
>> Thank you.<br>
>> Kind regards,<br>
>> Minh Phuong Nguyen<br>
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</blockquote></div>