<html><body><div style="color:#000; background-color:#fff; font-family:times new roman, new york, times, serif;font-size:14pt"><div><span><font size="4">Could anybody please help with the above questions? Or is it possible </font></span><span><font size="4"><font size="4"><span>to determine the position of the center of the cross section of the intestine at each slice/voxel, so that I can use the "Generic Move" in GATE to move the source in each time slice.</span></font></font></span></div><div style="color: rgb(0, 0, 0); font-size: 18px; font-family: times new roman,new york,times,serif; background-color: transparent; font-style: normal;"><br><span><font size="4"><font size="4"><span></span></font></font></span></div><div style="color: rgb(0, 0, 0); font-size: 18px; font-family: times new roman,new york,times,serif; background-color: transparent; font-style: normal;"><span><font size="4"><font size="4"><span>Thank you in
advance.<br></span></font></font></span></div><div style="display: block;" class="yahoo_quoted"> <br> <br> <div style="font-family: times new roman, new york, times, serif; font-size: 14pt;"> <div style="font-family: times new roman, new york, times, serif; font-size: 12pt;"> <div dir="ltr"> <font face="Arial" size="2"> On Monday, 10 March 2014 6:02 PM, Tony <tucadaica@yahoo.com> wrote:<br> </font> </div> <div class="y_msg_container"><div id="yiv2343922660"><div><div style="color:#000;background-color:#fff;font-family:times new roman, new york, times, serif;font-size:12pt;"><div></div><div>
<div class="yiv2343922660MsoNormal">Hi GATE users,</div><div class="yiv2343922660MsoNormal"><br></div>
<div class="yiv2343922660MsoNormal">I am trying to figure out if it would be possible to obtain
a 3D dose distribution map in a GATE simulation, in which a point source (geometric
source: <span style=""> </span>1mm-diameter sphere) moves along
a human gastro-intestinal tract. <br></div><div style="color:rgb(0, 0, 0);font-size:16px;font-family:times new roman, new york, times, serif;background-color:transparent;font-style:normal;" class="yiv2343922660MsoNormal"><br></div>
<div class="yiv2343922660MsoNormal">I have read the GATE user guide carefully, especially the
section about voxelized phantom and dose collection. However, since I am quite
new to the field of medical physics, there were many parts I could not
understand clearly.</div><div class="yiv2343922660MsoNormal"><br></div>
<div class="yiv2343922660MsoNormal">As far as I know, I would need to use a voxelized phantom,
such as the “Extended 4D NCAT Phantom” in which the gastro-intestinal tract is
also included. Then, a 1mm-diameter sphere source needs to be defined and it should
be able to move along the intestine. <span style=""><br></span></div><div style="color:rgb(0, 0, 0);font-size:16px;font-family:times new roman, new york, times, serif;background-color:transparent;font-style:normal;" class="yiv2343922660MsoNormal"><span style=""><br></span></div>
<div class="yiv2343922660MsoNormal">I have successfully run several GATE simulations in which a
geometric source moves in a basic trajectory inside a geometric phantom, but I
have never worked with a voxelized phantom and a complex movement of the source
before. <br></div><div class="yiv2343922660MsoNormal"><br></div>
<div class="yiv2343922660MsoNormal">My questions are:</div>
<div class="yiv2343922660MsoNormal"><span style="font-style:italic;">1) Would it be possible to produce such a 3D dose
distribution map in GATE when a 1mm-diameter spherical source moves along the
intestinal tract (assuming the source has a constant speed, approximately 8 hours
to complete its journey, similar to food excretion)?</span></div><div style="color:rgb(0, 0, 0);font-size:16px;font-family:times new roman, new york, times, serif;background-color:transparent;font-style:italic;" class="yiv2343922660MsoNormal"><span style="font-style:italic;"><br></span></div><span style="font-style:italic;">
</span><div class="yiv2343922660MsoNormal"><span style="font-style:italic;">2) Assume that I already got the Extended 4D NCAT Phantom,
how can I define the source movement so that the source can move along the
intestine of the phantom?</span></div><span style="font-style:italic;">
</span><div class="yiv2343922660MsoNormal"><span style="font-style:italic;"><br></span></div><div style="color:rgb(0, 0, 0);font-size:16px;font-family:times new roman, new york, times, serif;background-color:transparent;font-style:italic;" class="yiv2343922660MsoNormal"><span style="font-style:italic;">3) Does the 3D dose distribution map show the <span style="text-decoration:underline;">total absorbed
dose</span> deposited in every voxel of the NCAT phantom throughout 8 hour moving of
the source?</span></div>
<div class="yiv2343922660MsoNormal"><br></div><div style="color:rgb(0, 0, 0);font-size:16px;font-family:times new roman, new york, times, serif;background-color:transparent;font-style:normal;" class="yiv2343922660MsoNormal">Your help would be greatly appreciated. </div>
<div class="yiv2343922660MsoNormal">Thank you,</div>
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