<div dir="ltr"><div style="font-family:arial,sans-serif;font-size:13px">You need an optimization process to compute the weight (intensities) of all spots such that their weighted sum lead to the targeted SOBP. Such optimization is not provided with GATE, you need to refer a commercial TPS (Treatment Planning System) to read weights in the produced DICOM file, or implement your own. </div>
<div style="font-family:arial,sans-serif;font-size:13px"><br></div><div style="font-family:arial,sans-serif;font-size:13px">You can refer to this article to understand how to get that weight : <a href="http://www.ncbi.nlm.nih.gov/pubmed/11098905" target="_blank">http://www.ncbi.nlm.nih.gov/pubmed/11098905</a></div>
<div style="font-family:arial,sans-serif;font-size:13px"><br></div><div style="font-family:arial,sans-serif;font-size:13px">best, <br>David</div></div><div class="gmail_extra"><br><br><div class="gmail_quote">On Fri, Oct 18, 2013 at 7:31 AM, David Sarrut <span dir="ltr"><<a href="mailto:david.sarrut@gmail.com" target="_blank">david.sarrut@gmail.com</a>></span> wrote:<br>
<blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr"><div dir="auto"><div>You need an optimization process to compute the weight (intensities) of all spots such that their weighted sum lead to the targeted SOBP. Such optimization is not provided with GATE, you need to refer a commercial TPS (Treatment Planning System) to read weights in the produced DICOM file, or implement your own. </div>
<div><br></div><div>You can refer to this article to understand how to get that weight : <a href="http://www.ncbi.nlm.nih.gov/pubmed/11098905" target="_blank">http://www.ncbi.nlm.nih.gov/pubmed/11098905</a></div><div><br>
</div><div>best, <br>
David<div><br></div></div><div><br>Le 18 oct. 2013 à 00:08, Ahmed Elmekawy <<a href="mailto:ahmedfelmekawy@gmail.com" target="_blank">ahmedfelmekawy@gmail.com</a>> a écrit :<br><br></div><div><div class="h5"><blockquote type="cite">
<div>
<div dir="ltr">Dear All,<div><br></div><div>I know Jefferson is right, this is the definition for the SOBP to collect all pristine Bragg peak and defined the energy and weight factor for all peak i will use but my question how I can it by Gate,thanks.</div>
<div><br></div><div>Best Regards,</div><div>Ahmed </div></div><div class="gmail_extra"><br><br><div class="gmail_quote">On Thu, Oct 17, 2013 at 10:17 AM, Loic Grevillot <span dir="ltr"><<a href="mailto:loic.grevillot@gmail.com" target="_blank">loic.grevillot@gmail.com</a>></span> wrote:<br>
<blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left-width:1px;border-left-color:rgb(204,204,204);border-left-style:solid;padding-left:1ex"><div dir="ltr">Dear Ahmed,<div><br></div><div>Jefferson is right, a SOBP is simply a collection of Pristine Bragg peaks.</div>
<div>First you have to simulate a set depth-doses, with an energy step of a few MeV in between each energy (1 or 2 mm steps in range for instance between 2 peaks).</div>
<div>Then you have to sum the peaks with different weight in order to build a flat SOBP.</div><div><br></div><div>Sincerely,</div><div><br></div><div>Loïc</div><div><br></div></div><div class="gmail_extra">
<br clear="all"><div>Loïc<br></div><div><div>
<br><br><div class="gmail_quote">2013/10/17 Ahmed Elmekawy <span dir="ltr"><<a href="mailto:ahmedfelmekawy@gmail.com" target="_blank">ahmedfelmekawy@gmail.com</a>></span><br><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left-width:1px;border-left-color:rgb(204,204,204);border-left-style:solid;padding-left:1ex">
<div dir="ltr">Hi Jefferson,<div> </div><div>I used example 6 for the pencil proton beam,do you have any idea how I can make it,Thanks.</div><div><br></div><div>Best Regards,</div><div>Ahmed</div>
</div><div><div><div class="gmail_extra"><br><br><div class="gmail_quote">On Thu, Oct 10, 2013 at 4:22 PM, Jefferson <span dir="ltr"><<a href="mailto:jefferson.sorriaux@gmail.com" target="_blank">jefferson.sorriaux@gmail.com</a>></span> wrote:<br>
<blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left-width:1px;border-left-color:rgb(204,204,204);border-left-style:solid;padding-left:1ex"><div dir="ltr">Dear Ahmed,<div><br></div><div>You can do several simulations changing the energy of your incident protons and weight the simulation results (pristine bragg peak) at the end to obtain a flat sobp.</div>
<div><br></div><div>Regards,</div></div><div class="gmail_extra"><br><br><div class="gmail_quote">2013/10/10 Ahmed Elmekawy <span dir="ltr"><<a href="mailto:ahmedfelmekawy@gmail.com" target="_blank">ahmedfelmekawy@gmail.com</a>></span><br>
<blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left-width:1px;border-left-color:rgb(204,204,204);border-left-style:solid;padding-left:1ex"><div><div><div dir="ltr"><span style="font-family:arial,sans-serif;font-size:13px">Dear Gate User,</span><div>
<span style="font-family:arial,sans-serif;font-size:13px"> </span><div>
<span style="font-family:arial,sans-serif;font-size:13px">I just have a question about the sobp ?,I am trying to do the the sobp for the beam through the water phantom by Gate, I am able to do the pristine peak but how I can do the sobp by gate,</span><br>
</div></div><div><span style="font-family:arial,sans-serif;font-size:13px"><br></span></div><div><span style="font-family:arial,sans-serif;font-size:13px">Best Regards,</span></div><div><span style="font-family:arial,sans-serif;font-size:13px">Ahmed</span></div>
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</blockquote></div><br><br clear="all"><div><br></div>-- <br><div dir="ltr">David Sarrut, Phd<br>Directeur de recherche CNRS<br>CREATIS, UMR CNRS 5220, Inserm U 1044<div>Centre de lutte contre le cancer Léon Bérard<br>28 rue Laënnec, 69373 Lyon cedex 08<br>
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